Quarterly Publication Update March 2020

March 24, 2020

Every quarter we will be featuring recent publications by IIT-affiliated faculty, students and alumni; this is our first edition. Explore the links below to learn more about the exciting research happening at the IIT and MSU! 

• Bates MA, Benninghoff AD, Gilley KN, Holian A, Harkema JR, Pestka JJ. Mapping of Dynamic Transcriptome Changes Associated With Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse. Front Immunol. 2019 Mar 29;10:632. doi: 10.3389/fimmu.2019.00632. eCollection 2019. PubMed PMID: 30984195; PubMed Central PMCID: PMC6450439.
  
  
• Benninghoff AD, Bates MA, Chauhan PS, Wierenga KA, Gilley KN, Holian A, Harkema JR, Pestka JJ. Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus. Front Immunol. 2019 Dec 13;10:2851. doi: 10.3389/fimmu.2019.02851. PMID: 31921124; PMCID: PMC6923248.
  
  
• Benninghoff AD, Hintze KJ, Monsanto SP, Rodriguez DM, Hunter AH, Phatak S, Pestka JJ, Wettere AJV, Ward RE. Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice. Nutrients. 2020 Feb 20;12(2). pii: E544. doi: 10.3390/nu12020544. PubMed PMID: 32093192; PubMed Central PMCID: PMC7071445.
  
  
• Bernard JJ, Gallo RL, Krutmann J. Photoimmunology: how ultraviolet radiation affects the immune system. Nat Rev Immunol. 2019 Nov;19(11):688-701. doi:10.1038/s41577-019-0185-9. Epub 2019 Jun 18. Review. PubMed PMID: 31213673.
  
  
• Blevins LK, Zhou J, Crawford R, Kaminski NE. TCDD-mediated suppression of naïve human B cell IgM secretion involves aryl hydrocarbon receptor-mediated reduction in STAT3 serine 727 phosphorylation and is restored by interferon-γ. Cell Signal. 2020 Jan;65:109447. doi: 10.1016/j.cellsig.2019.109447. Epub 2019 Oct 31. PubMed PMID: 31678681; PubMed Central PMCID: PMC6903688. 
  
  
• Dornbos P, Arkatkar AA, LaPres JJ. An Automated Method To Predict Mouse Gene and Protein Sequences Using Variant Data. G3 (Bethesda). 2020 Mar 5;10(3):925-932. doi: 10.1534/g3.119.400983. PubMed PMID: 31911484; PubMed Central PMCID: PMC7056971.
  
  
• Dornbos P, Jurgelewicz A, Fader KA, Williams K, Zacharewski TR, LaPres JJ. Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice. Sci Rep. 2019 Nov 1;9(1):15828. doi: 10.1038/s41598-019-52001-2. PubMed PMID: 31676775; PubMed Central PMCID: PMC6825130.
  
  
• Groeneveld D, Cline-Fedewa H, Baker KS, Williams KJ, Roth RA, Mittermeier K, Lisman T, Palumbo JS, Luyendyk JP. Von Willebrand factor delays liver repair after acetaminophen-induced acute liver injury in mice. J Hepatol. 2020 Jan;72(1):146-155. doi: 10.1016/j.jhep.2019.09.030. Epub 2019 Oct 10. PubMed PMID: 31606553; PubMed Central PMCID: PMC6941657.
  
  
• Harkema JR, Eldridge EA, Lewandowski RP, Wagner JG. Influx, Persistence, and Recall of Eosinophils and GATA-3+ Innate Lymphoid Cells in the Nasal Mucosa of Mice Exposed and Reexposed to the Gaseous Air Pollutant Ozone. Toxicol Pathol. 2020 Feb;48(2):323-337. doi: 10.1177/0192623319882768. Epub 2019 Nov 15. PMID: 31729279.
  
  
• Kochmanski J, Bernstein AI. The Impact of Environmental Factors on 5-Hydroxymethylcytosine in the Brain. Curr Environ Health Rep. 2020 Feb 4. doi:10.1007/s40572-020-00268-3. [Epub ahead of print] Review. PubMed PMID: 32020534.
  
  
• Li J, Settivari RS, LeBaron MJ, Marty MS. Functional Comparison of HepaRG Cells and Primary Human Hepatocytes in Sandwich and Spheroid Culture as Repeated-Exposure Models for Hepatotoxicity. Applied In Vitro Toxicology. 2019 Dec; 5:4: 187-195.
  
  
• Pacyga DC, Henning M, Chiang C, Smith RL, Flaws JA, Strakovsky RS. Associations of Pregnancy History with BMI and Weight Gain in 45-54-Year-Old Women. Curr Dev Nutr. 2019 Dec 5;4(1):nzz139. doi: 10.1093/cdn/nzz139. eCollection 2020 Jan. PubMed PMID: 31893261; PubMed Central PMCID: PMC6933615.
  
  
• Smith AL, Paul E, McGee D, Sinniah R, Flom E, Jackson-Humbles D, Harkema J, Racicot KE. Chronic, Elevated Maternal Corticosterone During Pregnancy in the Mouse Increases Allergic Airway Inflammation in Offspring. Front Immunol. 2020 Jan 21;10:3134. doi: 10.3389/fimmu.2019.03134. PMID: 32038643; PMCID: PMC6985541.
  
  
• Vazquez-Cintron E, Machamer J, Ondeck C, Pagarigan K, Winner B, Bodner P, Kelly K, Pennington MR, McNutt P. Symptomatic treatment of botulism with a clinically approved small molecule. JCI Insight. 2020 Jan 30;5(2). pii: 132891. doi: 10.1172/jci.insight.132891. PubMed PMID: 31996484.
  
  
• Wang Z, Yang P, Xie J, Lin HP, Kumagai K, Harkema J, Yang C. Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression. Environ Int. 2020 Feb 13;137:105560. doi: 10.1016/j.envint.2020.105560. Epub ahead of print. PMID: 32062438.
  
  
• Wierenga KA, Harkema JR, Pestka JJ. Lupus, Silica, and Dietary Omega-3 Fatty Acid Interventions. Toxicol Pathol. 2019 Dec;47(8):1004-1011. doi: 10.1177/0192623319878398. Epub 2019 Nov 14. PubMed PMID: 31725357; PubMed Central PMCID: PMC6910909.
  
  
• Wierenga KA, Wee J, Gilley KN, Rajasinghe LD, Bates MA, Gavrilin MA, Holian A, Pestka JJ. Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal. Front Immunol. 2019 Sep 20;10:2130. doi: 10.3389/fimmu.2019.02130. eCollection 2019. PubMed PMID: 31616405; PubMed Central PMCID: PMC6763728.
  
  
• Zhou Y, Klinger GE, Hegg EL, Saffron CM, Jackson JE. Multiple Mechanisms Mapped in Aryl Alkyl Ether Cleavage via Aqueous Electrocatalytic Hydrogenation over Skeletal Nickel. J Am Chem Soc. 2020 Feb 26;142(8):4037-4050. doi: 10.1021/jacs.0c00199. Epub 2020 Feb 13. PubMed PMID: 32017546.
  
  
• Zhuang J, Cox JG, Chung M, Hamm JA, Zwickle A, Upham BL. Risk, Stigma, Trustworthiness, and Citizen Participation-A Multifaceted Analysis of Media Coverage of Dioxin Contamination in Midland, Michigan. Int J Environ Res Public Health. 2019 Oct 29;16(21). pii: E4165. doi: 10.3390/ijerph16214165. PubMed PMID: 31671717; PubMed Central PMCID: PMC6862584.
  
  
• Zwickle A, Cox JG, Zhuang J, Hamm JA, Upham BL, Chung M, Cruz S, Dearing JW. The Effect of Dioxin Contamination and Remediation on Property Values. Int J Environ Res Public Health. 2019 Oct 15;16(20). pii: E3900. doi:10.3390/ijerph16203900. PubMed PMID: 31618820; PubMed Central PMCID: PMC6843844.