Timothy R. Zacharewski
Hepatotoxicity
Endocrine Disruption/Bone
Biochemistry and Molecular Biology
- Professor, Department of Biochemistry and Molecular Biology
- Biochemistry
- 603 Wilson Rd Room 501A
- East Lansing MI 48824
- 517-355-1607
- tzachare@msu.edu
RESEARCH INTERESTS
Dr. Zacharewski works in the area of receptor mediated toxicology. In his laboratory, the primary focus is on mechanistic toxicology that involves elucidating how a chemical elicits its adverse effects. More specifically, he is interested in exploring how chemicals cause changes in gene expression that result in hormone-dependent cancers and compromised reproductive fitness. Research efforts are currently divided into the following two areas: endocrine disruption, to examine receptor-mediated endocrine disrupting activities of chemicals and natural products in humans and wildlife; and toxicogenomics, to assess the effects of developmental exposure to endocrine disruptors on fertility and reproductive tissue gene expression profiles using gene expression array technology developed as a result of the Human Genome Project.
EDUCATIONAL BACKGROUND
University of Guelph, Ontario, Canada, B.S., Chemistry with Microbiology Emphasis, 1986 Texas A&M University, Ph.D., Toxicology, 1990
AFFILIATED WEBSITES
https://bmb.natsci.msu.edu/faculty/timothy-r-zacharewski/
PUBLICATIONS
Dr. Zacharewski at PubMed
Dr. Zacharewski at MSU Scholars