Timothy R. Zacharewski

Timothy  R.  Zacharewski
  • Professor, Department of Biochemistry and Molecular Biology
  • Biochemistry
  • 603 Wilson Rd Room 501A
  • East Lansing MI 48824
  • 517-355-1607


Dr. Zacharewski works in the area of receptor mediated toxicology. In his laboratory, the primary focus is on mechanistic toxicology that involves elucidating how a chemical elicits its adverse effects. More specifically, he is interested in exploring how chemicals cause changes in gene expression that result in hormone-dependent cancers and compromised reproductive fitness. Research efforts are currently divided into the following two areas: endocrine disruption, to examine receptor-mediated endocrine disrupting activities of chemicals and natural products in humans and wildlife; and toxicogenomics, to assess the effects of developmental exposure to endocrine disruptors on fertility and reproductive tissue gene expression profiles using gene expression array technology developed as a result of the Human Genome Project.


University of Guelph, Ontario, Canada, B.S., Chemistry with Microbiology Emphasis, 1986 
Texas A&M University, Ph.D., Toxicology, 1990




Dr. Zacharewski at PubMed

Dr. Zacharewski at MSU Scholars