Rance Nault
- Assistant Professor, Department of Pharmacology and Toxicology
- Life Science
- 1355 Bogue St. Room B403
- East Lansing MI 48824
- 517-353-1944
- naultran@msu.edu
RESEARCH INTERESTS
My research is focused on using high throughput ‘omic’ and targeted phenotypic endpoints to examine the health consequences of exposure to environmental and food contaminants. Technological innovations have enabled researchers to evaluate hundreds to thousands of molecules in a single sample, and along with these new platforms comes the challenges of analyzing, interpreting, and integrating the large datasets. Through a combination of wet lab and computational approaches, I leverage these technologies to investigate mechanisms and dose-responses of liver toxicants. Two current major areas of emphasis are (1) the use of single-cell sequencing technology to refine our understanding of liver toxicity and (2) developing the framework to support the robust collection and sharing of high-quality data to promote reuse. The overarching long-term goal of my research is to accelerate the mechanistic understanding of toxicant induced liver injury and improve the translation to human risk.
EDUCATIONAL BACKGROUND
University of Ottawa, B.Sc., 2009, Biology
University of Ottawa, M.Sc., 2011, Physiology with specialization in Chemical and Environmental Toxicology
Michigan State University, Ph.D., 2016, Biochemistry and Molecular Biology and Integrative Toxicology