Jack R. Harkema
- University Distinguished Professor, The Albert C. and Lois E. Dehn Endowed Chair in Veterinary Medicine, Department of Pathobiology & Diagnostic Investigation
- Director of the Laboratory for Environmental & Toxicologic Pathology and the Mobile Air Research Laboratories (AirCARE 1 and 2) at Michigan State University
- Food Safety
- 1129 Farm Ln Room 212
- East Lansing MI 48824
- 517-353-8627
- harkemaj@msu.edu
RESEARCH INTERESTS
- Understanding the pathologic basis of health effects caused by environmental and occupational air pollutants
- Using laboratory animal models of respiratory, cardiovascular, autoimmune and metabolic diseases to explore how chronic diseases affect susceptibility to toxicity caused by inhaled toxicants (ozone, particulate matter and silica dust)
- With the overall goal to experimentally elucidate cellular, molecular or biochemical targets for interventions to prevent or treat adverse effects caused by air pollution
Current Investigation
- Role of group 2 innate lymphoid cells (ILC2s) in air pollutant-induced, allergen-independent asthma and rhinitis
- Mechanisms of dietary lipid prevention/treatment for silica-induced autoimmunity
- Airway and systemic inflammatory/immune responses to short-and long-term exposures to ambient air pollutants individually or as mixtures
EDUCATIONAL BACKGROUND
Calvin College, B.S., Biology/Chemistry, 1975
Michigan State University, M.S., Physiology, 1977
Michigan State University, D.V.M., cum laude, 1980
University of California-Davis, Ph.D., 1985, Comparative Pathology
AFFILIATED WEBSITES
https://cvm.msu.edu/directory/harkema
https://research.msu.edu/tag/jack-harkema/