Lyle D. Burgoon

Lyle D.  Burgoon
  • Adjunct Associate Professor, Institute for Integrative Toxicology
  • Director, Center for Existential Threat Analysis and Leader, Bioinformatics and Computational Toxicology
  • US Army Engineer Research and Development Center


Dr. Burgoon's primary research interests focus on: 1) applied toxicology and risk assessment in the military environment (toxic industrial chemicals, CBRNE (chemical, biological, radiological, nuclear, and high yield explosive) weapons of mass destruction), 2) applied toxicology and risk assessment of civilian accidental releases and mass casualty events, 3) predictive computational toxicology, physiologically-based pharmacokinetic modeling (PBPK) and artificial intelligence, and 4) applied biostatistics in toxicology and chemical/drug safety assessment (i.e., metascience applied to toxicology). Dr. Burgoon's research programs are funded by the US Defense Threat Reduction Agency, the Office of the Secretary of Defense, and the US Army Futures Command. Dr. Burgoon has recently started a research program focused on metascience applied to toxicology -- specifically, studying how defects in study designs, psuedoreplication and sample bias are contributing to the replication crisis in toxicology, and how these defects impact safety/risk assessments, policies, and drug/chemical regulations. 


Augustana College, A.B., 1999, Pre-Medicine and Biology

Michigan State University, Ph.D., 2005, Department of Pharmacology & Toxicology with Environmental Toxicology

Michigan State University, Biochemistry & Molecular Biology, Postdoctoral


Dr. Burgoon at PubMed