Patricia E. Ganey
- Professor Emeritus, Department of Pharmacology and Toxicology
- Food Safety
- 1129 Farm Ln Room 214
- East Lansing MI 48824
- 517-432-1761
- ganey@msu.edu
RESEARCH INTERESTS
Dr. Ganey's research interests lie in the interaction of inflammation and chemically induced liver injury. For many chemicals of diverse structure and mechanism of action, ongoing inflammation makes the liver more sensitive to toxic effects. Among the chemicals for which this is true are some drugs and environmental contaminants. Dr. Ganey’s research focus is on understanding the mechanisms by which inflammation causes this change in sensitivity. She studies inflammatory cells, including neutrophils and liver macrophages, as well as soluble mediators, like cytokines. A current project is aimed at development of assays that identify drugs that have the potential to cause idiosyncratic liver injury in people. She also collaborates with Dr. Atchison to understand the role of reactive oxygen species in the interaction of methyl mercury and amyotrophic lateral sclerosis (ALS).
EDUCATIONAL BACKGROUND
University of Maryland, B.S., 1979, Biological Sciences
Michigan State University, Ph.D., 1986, Pharmacology/Toxicology
AFFILIATED WEBSITES
https://phmtox.msu.edu/people/faculty/ganey/