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Tox Track, 10/10/16

Weekly Newsletter of the MSU Institute for Integrative Toxicology
Director: Dr. Norbert Kaminski / Editor: Lauren St.John

October 10, 2016, Vol. 39, Number 20

Seminars / Events / Symposiums / Job Postings



Friday, October 14
*The Institute for Integrative Toxicology presents EITS students Kelly Fader and Joe Zagorski to give a seminar on Friday, October 14, 2016, at 12 noon in 162 Food Safety and Toxicology Building. Fader will speak on, “Dysregulation of Iron Homeostasis and Heme Metabolism in TCDD-Elicited Hepatotoxicity.” Zagorski will speak on, “Nrf2-dependent and –Independent Effects of tBHQ and CDDO-Im in Jurkat T cells as determined by CRISPR/Cas-9 gene editing.”

Thursday, October 20
*The Respiratory Research Initiative presents Dr. Mikhail A. Gavrilin, Davis Heart and Lung Research Institute, Ohio State University, to speak on, “Inflammasome priming, assembly and activation,” on Thursday, October 20, 2016 at 11:30 a.m. in 162 Food Safety and Toxicology Building.

Thursday, October 20
*The Respiratory Research Initiative presents Dr. Katherine Zychowski, University of New Mexico, to speak on, “Cardiovascular and Respiratory Effects from Pulmonary Exposure to Metal-Contaminated Dusts from an Abandoned Uranium Mine,” on Thursday, October 20, 2016 at 3:30 p.m. in 162 Food Safety and Toxicology Building.

Thursday, November 3
*The Department of Physiology presents Dr. Andrew Eagle, postdoctoral fellow, to speak on, “Circuit-specific hippocampal gene expression in psychiatric disease,” on Thursday, November 3, 2016, at 4 p.m. in 1425 Biomedical Physical Science Building.

Wednesday, November 30
*The Department of Pharmacology and Toxicology presents Dr. Cheryl Rockwell, to speak on, “The role of Nrf2 in immune cell function,” on Wednesday, November 30, 2016, at 12 noon in B448 Life Science Building.

Friday, December 2
*The Department of Pharmacology and Toxicology presents Dr. Eran Andrechek, to speak on, “Using genomics to predict optimal therapy in a mouse model of breast cancer,” on Friday, December 2, 2016, at 9 a.m. in B448 Life Science Building.

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs. Seminars that fulfill this requirement are archived at:


EITS Research Evening
The Institute for Integrative Toxicology will host our annual Research Evening to showcase trainees in the Environmental and Integrative Toxicological Sciences Training Program and their accomplishments on Wednesday, November 30, 2016, 5:15 to 8:00 p.m., in the Lincoln Room of the MSU Kellogg Center. The event will include dinner, student presentations and a poster session. Please RSVP by November 18 to Kasey Baldwin, or call 353-6469. 



4th Annual ESPP Research Symposium: Environmental Health

November 11, 2016, Kellogg Hotel and Conference Center, MSU

This symposium is a student organized event which brings together students from a range of disciplines across MSU campus to present their research in a public forum and explore interdisciplinary collaboration between graduate students, faculty, and community stakeholders. Over the past three years, this annual event has been a major success drawing 298 attendees from at least six different colleges within MSU along with a significant number of participants from other universities, government, private sector, and general public. Our theme for the 4th annual symposium is Environmental Health. As defined by the World Health Organization, environmental health “encompasses the assessment and control of those environmental factors that can potentially affect health. It is targeted towards preventing disease and creating health-supportive environments”. Our vision for the event is to bring together multiple communites on campus that are working on different aspects of environmental health to share their experiences and identify collaborative opportunities. We plan to have four sessions – two concurrent sessions in the morning and two in the afternoon with three keynotes, a poster session, and a podium lightning session that consists of short 5-minute presentations with project highlights. Both of the afternoon sessions and at least one keynote lecture will cover multidisciplinary topics relevant to the Flint water crisis including, but not limited to engineering, policy, public health, and risk communication and management.

For more information and to register:


Job Postings

Postdoctoral Research Position in Ecosystem Service Valuation
A joint postdoctoral position is available at the School for the Environment at the University of Massachusetts Boston and the Environmental Studies Program at Dartmouth College for a motivated candidate with expertise in ecosystem service valuation. The successful candidate will join a transdisciplinary team of natural and social scientists working on a recently funded project that seeks to develop a framework for linking the health of small streams to water quality indicators, ecosystem services, and human preferences.
The successful candidate will work with Professor Richard B. Howarth (Dartmouth College) and Assistant Professor Georgia Mavrommati (University of Massachusetts Boston) to apply multiple methods (e.g. discourse-based decision analysis and choice modelling) to characterize and value ecosystem services.

Candidates should have a Ph.D. in environmental/ecological economics, decision science, or a related field and a motivation to develop cross-disciplinary approaches within social-ecological systems and sustainability science research. Applicants’ experience, ability and willingness to work with a transdisciplinary team and stakeholders is an asset. We offer a two-year appointment and a competitive salary plus health benefits. The starting date is flexible, but the expected start day is February, 2017.

Interested applicants should send a curriculum vita, a cover letter and the names and e-mail addresses of three referees combined in a single pdf to Dr. Georgia Mavrommati (Email: by November 1, 2016.

For questions about this position, please email to Dr. Georgia Mavrommati (

Program Officer in Data Science at the NIEHS
The Division of Extramural Research and Training (DERT) of the National Institute of Environmental Health Sciences (NIEHS), located in Research Triangle Park, NC, is recruiting a dynamic and experienced scientist with expertise in the application of data science tools and approaches to biomedical research. The advent of ‘Big Data’ brings special challenges and opportunities for environmental health sciences, as heterogeneous exposure and biologic data streams must be brought together to understand the interaction of genetic and environmental factors in complex human disease etiology.  The successful candidate will have interest in leading the development of programs to catalyze a transformation of environmental health sciences research to make data more findable, accessible, interoperable, and reusable (FAIR).

The candidate for this specific position will have responsibility for building and managing a portfolio of research grants in one or more specific areas of data science (e.g., bioinformatics tools and resources for toxicology), leading the overall development of NIEHS extramural initiatives to encourage greater data access and sharing, coordinating data science activities across the division, serving as a resource for data management issues within multiple collaborative research programs at NIEHS, and participating in trans-NIH data science programs.

Contact Cindy Lawler at for more information. Note that the closing date is October 12th.

Interested applicants can apply through USA Jobs under the posting for Health Scientist Administrator (Program Officer) – GS-0601-12/13/14: (Open to all U.S. Citizens); NIH-GR-DE-17-1794573

Postdoctoral Fellowship, The University of Texas at Austin
Evaluation of the contribution of the innate immune system to testicular toxicity induced by exposure to

A postdoctoral fellowship is available to investigate the contribution of the innate immune system (macrophages, monocytes, neutrophils, natural killer and dendritic cells) in the loss of testicular germ cells from the postnatal male testis after exposure to the phthalate class of environmental toxicants. The goal of the project is to decipher the cellular signals that instigate leukocyte infiltration into the testis after exposure to mono-(2-ethylhexyl) phthalate (MEHP) and to determine the functional significance of these cells in the pathogenesis of MEHP-induced germ cell apoptosis. It is predicted that insights gained from this work will be useful for predicting susceptible individuals and preventing human reproductive health risks this class of chemicals.

This position is available immediately and is supported by a NIH/NIEHS R01 grant funded through 11/30/2019.

Required qualifications: PhD within the last three years in the biological sciences (e.g., biochemistry, cell and molecular biology, immunology, pharmacology, toxicology).

Preferred qualifications: Strong background in immunology or reproductive biology; interest in the influence of environmental toxicant exposure on male fertility; experimental aptitude in fundamental skills such as western blot analysis, quantitative PCR, immunohistochemistry and working with rodents. These qualifications are tangibly indicated by a strong publication record by the applicant.

For consideration, please email ( a cover letter, curriculum vitae and a list of three references.

For more information, visit the laboratory web site:


ORISE Community Outreach Fellow, EPA

A postgraduate research training opportunity is currently available with EPA’s Region 5 Superfund Program. The appointment will be served with the Community Information Office in Flint, MI.

The research participant will be mentored by the Community Involvement Coordinator (CIC) stationed in the Flint office. Sites assigned to the Flint CIC include EPA’s Flint Drinking Water Response, Tittabawassee River/Saginaw River/Saginaw Bay Cleanup Site (Midland, Saginaw, Bay Counties), Allied Paper/Portage Creek/Kalamazoo River Cleanup Site (Kalamazoo, MI), Velsicol Chemical Cleanup Site (St. Louis, MI) and a number of other sites within Michigan.

The participant will be involved in a variety of environmental communication and education activities, including the maintenance of a robust innovative outreach program, including developing site outreach materials, and implementing community involvement activities.

For more information and to apply, please visit:

Radon and Indoor Air Program manager/Environmental Administrator, Florida Department of Health

General administrative and managerial duties:

  • Program administrator for radon and indoor air program;
  • Direct, coordinate, facilitate activities of 5 technical and 2 support staff;
  • Work with staff to develop program plans and functions;
  • Approve and direct implementation of finalized program plans;
  • Manage program budget and direct program response to emerging public health issues.

Program technical duties:

  • Serve as program lead technical specialist on radon;
  • Provide technical expertise for national radon work groups of state representatives that 1) develop model state codes and policies and 2) work with federal agencies to review and comment on federal policies and guidance; plan, design and propose projects for grant funding to federal agencies;
  • Evaluates the measurement and mitigation efforts to explain and detail program’s progress and findings.  Reviews and evaluates reports of special investigations for federal agencies.
  • Identify proposed state legislation with the potential to impact program activities;
  • Coordinate or perform bill analysis;
  • Coordinate changes to proposed legislation and policy changes for department approval
  • Provide direct technical and advisory service to the public, business and government on radon and indoor air as needed.
  • Serves as expert witness on administrative hearings

For more information and to apply by October 18, please visit:

This newsletter is produced and distributed weekly by the Institute for Integrative Toxicology. To be added to the email list or to make suggestions regarding information that might be included in this publication, contact: Lauren St.John, Editor, Institute for Integrative Toxicology,