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Tox Track, 2/6/17

Weekly Newsletter of the MSU Institute for Integrative Toxicology
Director: Dr. Norbert Kaminski / Editor: Lauren St.John

February 6, 2017, Vol. 40, Number 3

Seminars / Events / Courses / Fellowships / Job Postings


Friday, February 17
*The Institute for Integrative Toxicology presents Dr. Robert Roth, MSU, to speak on, “Drug cytokine interaction in idiosyncratic, drug-induced liver injury,” on Friday, February 17, 2017, at 12 noon in 162 Food Safety and Toxicology Building.

Thursday, February 23
*The Respiratory Research Initiative presents Dr. James Pestka, MSU, to speak on, “Dietary Lipids and Silica-Triggered Autoimmunity,” on Thursday, February 23, 2017, at 11:30 a.m. in 162 Food Safety and Toxicology Building.

Wednesday, March 29
*The Department of Pharmacology and Toxicology presents Dr. Richard Judson, U.S. EPA, to speak on, “Alternative Approaches to Chemical Risk Assessment: Assays, Databases, Models,” on Wednesday, March 29, 2017, at 12 noon in B448 Life Science Building.

Thursday, April 6
*The Respiratory Research Initiative presents Drs. Melissa Millerick-May and Ken Rosenman, MSU, to speak on, “Hypersensitivity Pneumonitis,” on Thursday, April 6, 2017, at 11:30 a.m. in 162 Food Safety and Toxicology Building.

Thursday, April 20
*The Respiratory Research Initiative presents Dr. James Wagner, MSU, to speak on, “Inhalation of Contaminated Mine Waste Dusts as a Route for Systemic Metal Toxicity,” on Thursday, April 20, 2017, at 11:30 a.m. in 162 Food Safety and Toxicology Building.

Thursday, April 27
*The Respiratory Research Initiative presents Drs. Linda Mansfield and Susan Ewart, MSU, to speak on, “Defining the Role of the Early Infant Microbiome in Mediating Allergic Outcomes Associated with Asthma in a Mouse Model,” on Thursday, April 27, 2017, at 11:30 a.m. in 162 Food Safety and Toxicology Building.

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs. Seminars that fulfill this requirement are archived at:



SOT Alumni and Friends Reception
Current and former students, postdocs, faculty and friends of Michigan State University are invited to gather at a reception to be held at the 56th Annual Society of Toxicology Meeting in Baltimore, Maryland.  It will take place at the Hilton Baltimore on Tuesday evening, March 14, 2017, in the Tubman AB room, from 9:00-11:00 p.m. Dessert and coffee will be served.



Computational Systems Biology and Dose Response Modeling Short Course, PHM 980, Section 301, 1 credit
*Fulfills the EITS Topics in Toxicology requirement*

Date: May 15-17, 2017 (2.5 days)

Location: Food Safety and Toxicology Building, Room 162

Instructors: Sudin Bhattacharya, Michigan State University; Wan-Yun Cheng, US Environmental Protection Agency; Rory B. Conolly, US Environmental Protection Agency; Qiang Zhang, Emory University

Course Description: This short course will cover dynamical systems modeling techniques for quantitative investigation of how biological systems respond to
perturbations at the cellular level. The course will consist of lectures and hands-on computer simulation exercises on:

  • Common network motifs in signal transduction and gene regulatory networks that underlie systems-level cellular behaviors including homeostasis, adaptation, threshold response, binary and irreversible cell fate decisions, and oscillations.
  • How molecular circuits comprimising genes and proteins give rise to various dynamic and dose-response behaviors. Examples include cellular stress response, cell differentiation, and cell cycle and checkpoint control, etc.
  • Use of these simulation techniques to develop computational models for understanding and predicting nonlinear dose response behaviors of environmental toxicants and drugs.

Students will be required to bring a PC laptop computer (Mac is not recommended for compatability issues in some simulation exercises) each day to the course to run computer simulation exercises.

Please contact Dr. Qiang Zhang ( if you have any course-specific questions.

Please contact Steve Stofflect,, in the Department of Pharmacology and Toxicology for course registration/override. NOTE: While the course is offered during the summer semester, you will have to actually enroll in it for fall semester 2017.  



Fulbright-Hays Fellowship
The Fulbright-Hays competition is now open for doctoral students to do dissertation research in one or more countries with which the U.S. has diplomatic relations, except those of Western Europe, although shorter periods of the grant are allowed in Western Europe to consult relevant sources.  This fellowship covers airfare, insurance, and project expenses for the fellow and maintenance stipends for the fellow and accompanying dependents.

In this competition, advanced doctoral students apply through the project director at their institution of higher education (IHE) and the IHE submits the all the applications together and administers the grant on behalf of the student applicants who have been selected. 
MSU has been successful in this competition, largely due to the high quality of its graduate students and the attentive mentorship by the graduate faculty. 2016 was typical: we submitted 12 applications and were awarded 4 grants—one for Zanzibar, one for Senegal, Guinea-Bissau, and Portugal, one for Senegal and France, and one for Kazakhstan and Russia.

A student is eligible to apply who

  • is a citizen, national, or permanent resident of the United States,\
  • is a doctoral student in good standing at or near candidacy status,
  • is planning a teaching career in the United States upon completion of his or her doctoral program, and
  • possesses sufficient foreign language skills to carry out the dissertation research project. 

This year's competition closes March 14. Our internal deadline will be March 9, though there will be intermediate target dates for the various components of the application. For more information, please contact, Roger Bresnahan, Professor and Fulbright Program Advisor, at or

ILSI North America 2017 Summer Fellowship Program, ILSI North America Technical Committee on Food and Chemical Safety

The ILSI North America Technical Committee on Food and Chemical Safety will apply read across approaches for food related chemicals to understand their potential use in food safety assessment for the ILSI North America 2017 summer fellowship program. The selection of the candidate will depend on the candidate’s qualifications and experience in toxicology, risk assessment, and food safety.

Selection Criteria
A strong background in toxicology, risk assessment, food science, biostatistics and/or chemistry is required. A third or fourth year doctoral student is desired.

Applicants should have good written and oral communication skills and strong computer skills (spreadsheet, graphics, presentation, Internet, and statistical programs), and should also be organized, self-motivated, flexible, and able to work independently and interact with a variety of people. Other selection criteria may be added based on the specifics of the program, such as an interest in food safety.

Program Duration
The estimated time period for the program is 10 to 12 weeks during the spring/summer (May-Aug) of 2017. Alternative start and end dates are negotiable. Two days of vacation will be permitted.

The fellow will be provided with a stipend intended to cover expenses including transportation to/from Washington DC and housing.

Application Instructions
Candidates should submit a statement about how their background, experience and interests align with this project; a resume, including service and volunteer activities; an official transcript; and two letters of recommendation. Materials can be submitted to Dr. Mansi Krishan at Interviews (via phone) of prospective candidates will be arranged. Deadline for submission is Friday 10 February 2017.
For more information, please contact Dr. Mansi Krishan at


Job Postings

Multiple Positions Open, MI Public Health Institute

The Michigan Department of Health and Human Services is seeking scientific talent. We’re hiring through our partners, the Michigan Public Health Institute, but you’ll be working in Lansing with a great team of public health professionals on myriad environmental health topics. We will keep these positions posted until we find the right candidates.
Note, we will consider all eligible candidates for all of these positions regardless of the position title selected and applied for.

Positions are posted at

The following positions are available:
Toxicologist -posted 01/23/2017
Public Health Scientist -posted 01/23/2017
Environmental Scientist -posted 01/23/2017

To apply, please scroll further down the page at to “How to apply.”  You will have to register with MPHI’s E-Recruitment system and there is a link for information on that step.

Assistant Professor (Tenure-track): Toxicology and Safety of Food Packaging

Position: The School of Packaging ( in the College of Agriculture and Natural Resources at Michigan State University (MSU) is seeking qualified applicants for an Assistant Professor. This is a tenure-track position with a research/teaching/service (65%/25%/10%) assignment and can begin as early as August 2017. The successful candidate will be expected to develop an externally funded research program with a focus on areas such as identification and monitoring the toxicity of chemicals present in packaging systems, evaluating their interaction with food products, developing strategies to detect and assess additives or predicting the safety of additives through modeling.

Responsibilities: The individual will be expected to develop a nationally and internationally recognized research program in the area of toxicology as it relates to safety of food packaging. Research should use both basic science and applied approaches while addressing the issues and opportunities facing the packaging and food industry. The successful candidate will be expected to collaborate in research with the Center for Research on Ingredient Safety (CRIS) and the Institute for Integrative Toxicology. Other potential collaborators include Food Science and Human Nutrition, Biosystems and Agricultural Engineering, Biochemistry, and Molecular Biology. MSU strongly encourages such collaborations. Research support facilities available include Bioinformatics, Flow Cytometry, Genomics, IVIS Imaging, Mass Spectrometry, and Proteomics, among others.

The successful candidate will provide vision and leadership at the interface between packaging and toxicology. The candidate will develop an innovative research program, secure competitive external grant funding, publish in high quality peer-reviewed journals, mentor graduate and undergraduate students, provide leadership and service in professional scientific associations, and establish strong ties with the private sector. The candidate should demonstrate interest in excellence of teaching. The initial teaching assignment will involve contributing to relevant graduate or undergraduate packaging courses.

Qualifications: Candidates must have the following qualifications: a) a doctoral degree in toxicology, biochemistry, risk assessment, food science, or a closely related field; b) demonstrated capability to conduct independent research; c) the ability to work collaboratively with research teams; and d) excellent oral and written communication skills. Demonstration of impactful research and promise of research funding are important selection criteria.

Application Procedure: Qualified applicants should submit a) a letter of application, b) a summary of research accomplishments and a statement of research direction and interest (limited to 2 pages), c) a current curriculum vitae, d) a statement of Teaching Philosophy (limited to 1 page), e) a summary of experience with diversity in the classroom and/or research endeavors, any experience in mentoring diverse students, and an explanation of how you will contribute to our goals of inclusive excellence (limited to 1 page), and f) the names and email addresses of three references online at (posting #_4535) .Review of applications will begin on (March 1, 2017) and will continue until the position is filled. Inquiries about the position should be addressed to Dr. Maria Rubino, Search Committee Chair, School of Packaging, Michigan State University, East Lansing MI 48824-1325. Telephone 517 355-0172, E-mail:

Environmental Toxicologist, College of Public Health, Ohio State University

The College of Public Health and the College of Food, Agriculture & Environmental Sciences at The Ohio State University invites applications for a tenure track/tenured position in the fields of environmental toxicology, developmental toxicology or environmental health science at the assistant, associate or full professor level to commence autumn semester 2017. The ideal candidate will have experience and interests in environmental and/or dietary toxins/toxicants, such as heavy metals, smoke metabolites or biological toxins, with interest in modulating disease processes by dietary interventions or other nutritional integrating strategies. Experience in pre-clinical or clinical studies involving metabolic profiling or metabolomic techniques and bioinformatics is of particular interest.

The candidate must demonstrate the ability and interest in collaborating across disciplines, especially with OSU Comprehensive Cancer Center scientists and faculty in the College of Medicine and College of Education & Human Ecology. Applied technologies could include generating large data sets that rely on data analytics and bioinformatics to explore important dietary and/or environmentally related diseased states. The candidate will also teach undergraduate or graduate level classes related to the candidate's areas of expertise. Joint appointments are possible and actively encouraged with other disciplines at OSU.

This position is partially funded by Ohio State's Discovery Themes Initiative “Food to Improve Health” which is assembling a critical mass of scholars focused on the Food and Nutritional Metabolomics for Health. The overarching goal of this initiative is to increase understanding of individual biochemical variability in response to diet- and food-based interventions to improve health and prevent disease, and as a sound basis for appropriate dietary recommendations and public health messages.

Applicants are expected to have a Ph.D. or other doctoral degree in Environmental Health, Toxicology, Biochemistry, Chemistry, Food Science or a related field, by the start of employment, and to present evidence of excellence in teaching and research. Postdoctoral training is preferred. Appointment is contingent on the university’s verification of credentials and other information required by law and/or university policies, including but not limited to a criminal background check.

Application Instructions:
Applications will be accepted until the position is filled, but those received by February 15, 2017 will receive priority consideration. Applicants are asked to submit a cover letter including a statement of research and teaching interests, a current curriculum vitae, and copies of two (2) recent publications. Finalist candidates will be asked to supply letters of recommendation.

Applications are accepted through Academic Jobs Online:

This newsletter is produced and distributed weekly by the Institute for Integrative Toxicology. To be added to the email list or to make suggestions regarding information that might be included in this publication, contact: Lauren St.John, Editor, Institute for Integrative Toxicology,