Barbara Lee Faubert Kaplan
Assistant Professor, Institute for Integrative Toxicology
1129 FARM LN ROOM 313
EAST LANSING MI 48824
Dr. Kaplan’s research interest is elucidation of the mechanism by which cannabinoid compounds, derived from marijuana, affect immune function. She is interested in how the non-psychoactive cannabinoid, cannabidiol, suppresses T cell function through the inhibition of NFAT. She is also interested in the role of neuroimmune interactions in immune suppression by cannabinoids. An understanding of these mechanisms can help in development of drugs for the treatment of autoimmune disesases, such as multiple sclerosis. Dr. Kaplan is a co-investigator on four projects: IL-2 Suppression by Endocannabinoid Activation of PPARy; Tetrahydrocannabinol Impairment of CD4/CD8 T Cell-Mediated Host Resistance to HIV and Influenza; Immunotoxicology of Chronic Exposure to Estrogenic Bisphenol-A; and Environmental, Microbial, and Mammalian Biomolecular Responses to AhR Ligands.
University of California, Davis, B.S., Environmental Toxiocology, 1992
Michigan State University, Ph.D., Pharmacology and Toxicology, 2001
Selected Professional Activities:
Dr. Kaplan is a member of the Society of Toxicology and its Immunology Specialty Section. In March 2012, she received the Outstanding Young Investigator Award from the Immunotoxicology Specialty Section of the Society of Toxicology. She was a post-doctoral research associate at the University of Chicago, Department of Surgery and was previously employed as a chemist.
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