Patricia E. Ganey
Professor of Pharmacology and Toxicology
1129 FARM LN ROOM 214
EAST LANSING MI 48824
Dr. Ganey's research interests lie in the interaction of inflammation and chemically induced liver injury. For many chemicals of diverse structure and mechanism of action, ongoing inflammation makes the liver more sensitive to toxic effects. Among the chemicals for which this is true are some drugs and environmental contaminants. Dr. Ganey’s research focus is on understanding the mechanisms by which inflammation causes this change in sensitivity. She studies inflammatory cells, including neutrophils and liver macrophages, as well as soluble mediators, like cytokines. A current project is aimed at development of assays that identify drugs that have the potential to cause idiosyncratic liver injury in people. She also collaborates with Dr. Atchison to understand the role of reactive oxygen species in the interaction of methyl mercury and amyotrophic lateral sclerosis (ALS).
University of Maryland, B.S., 1979, Biological Sciences
Michigan State University, Ph.D., 1986, Pharmacology/Toxicology
Selected Professional Activities:
Dr. Ganey has received the following honors: Hazelton Laboratories Corporation Predoctoral Fellowship, 1984; National Research Service Award, 1987-89; American Liver Foundation Postdoctoral Fellowship, 1987; Past President of the Michigan Regional Chapter of the Society for Toxicology, 2000-2001; the Pfizer Excellence in Research Award, 2002; Secretary-Treasurer, Toxicology Division, American Society of Pharmacology and Experimental Therapeutics, 2002-2004; Society of Toxicology Awards Committee, 2006-2008; Chair of the Society of Toxicology Member Services Strategy Committee, 2006; Councilor, Society of Toxicology, 2008-2010; Chair-Elect, Toxicology Division, American Society of Pharmacology and Experimental Therapeutics, 2010; Chair, Toxicology Division, American Society of Pharmacology and Experimental Therapeutics, 2011; Secretary-Treasurer, Mechanism Specialty Section, Society of Toxicology, 2010-2012; Presidential chain of the Society of Toxicology, 2015-2019. She completed postdoctoral training at the University of North Carolina, Chapel Hill. Dr. Ganey belongs to the American Society for Pharmacology and Experimental Therapeutics and the Society of Toxicology. Dr. Ganey is a faculty trainer for the NIEHS training grant.
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